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1.
Viruses ; 15(9)2023 09 13.
Article in English | MEDLINE | ID: mdl-37766323

ABSTRACT

Singapore experiences endemic dengue. Vector control remains the primary means to reduce transmission due to the lack of available therapeutics. Resource limitations mean that vector-control tools need to be optimized, which can be achieved by studying risk factors related to disease transmission. We developed a statistical modelling framework which can account for a high-resolution and high-dimensional set of covariates to delineate spatio-temporal characteristics that are associated with dengue transmission from 2014 to 2020 in Singapore. We applied the proposed framework to two distinct datasets, stratified based on the primary type of housing within each spatial unit. Generalized additive models reveal non-linear exposure responses between a large range of ecological and anthropogenic factors as well as dengue incidence rates. At values below their mean, lesser mean total daily rainfall (Incidence rate ratio (IRR): 3.75, 95% CI: 1.00-14.05, Mean: 4.40 mm), decreased mean windspeed (IRR: 3.65, 95% CI: 1.87-7.10, Mean: 4.53 km/h), and lower building heights (IRR: 2.62, 95% CI: 1.44-4.77, Mean: 6.5 m) displayed positive associations, while higher than average annual NO2 concentrations (IRR: 0.35, 95% CI: 0.18-0.66, Mean: 13.8 ppb) were estimated to be negatively associated with dengue incidence rates. Our study provides an understanding of associations between ecological and anthropogenic characteristics with dengue transmission. These findings help us understand high-risk areas of dengue transmission, and allows for land-use planning and formulation of vector control policies.


Subject(s)
Dengue , Humans , Incidence , Singapore/epidemiology , Anthropogenic Effects , Models, Statistical
2.
IEEE Trans Vis Comput Graph ; 16(6): 1413-20, 2010.
Article in English | MEDLINE | ID: mdl-20975182

ABSTRACT

Over the past few years, large human populations around the world have been affected by an increase in significant seismic activities. For both conducting basic scientific research and for setting critical government policies, it is crucial to be able to explore and understand seismic and geographical information obtained through all scientific instruments. In this work, we present a visual analytics system that enables explorative visualization of seismic data together with satellite-based observational data, and introduce a suite of visual analytical tools. Seismic and satellite data are integrated temporally and spatially. Users can select temporal ;and spatial ranges to zoom in on specific seismic events, as well as to inspect changes both during and after the events. Tools for designing high dimensional transfer functions have been developed to enable efficient and intuitive comprehension of the multi-modal data. Spread-sheet style comparisons are used for data drill-down as well as presentation. Comparisons between distinct seismic events are also provided for characterizing event-wise differences. Our system has been designed for scalability in terms of data size, complexity (i.e. number of modalities), and varying form factors of display environments.

3.
IEEE Trans Vis Comput Graph ; 15(6): 1001-8, 2009.
Article in English | MEDLINE | ID: mdl-19834165

ABSTRACT

In this paper, we present a novel parallel coordinates design integrated with points (Scattering Points in Parallel Coordinates, SPPC), by taking advantage of both parallel coordinates and scatterplots. Different from most multiple views visualization frameworks involving parallel coordinates where each visualization type occupies an individual window, we convert two selected neighboring coordinate axes into a scatterplot directly. Multidimensional scaling is adopted to allow converting multiple axes into a single subplot. The transition between two visual types is designed in a seamless way. In our work, a series of interaction tools has been developed. Uniform brushing functionality is implemented to allow the user to perform data selection on both points and parallel coordinate polylines without explicitly switching tools. A GPU accelerated Dimensional Incremental Multidimensional Scaling (DIMDS) has been developed to significantly improve the system performance. Our case study shows that our scheme is more efficient than traditional multi-view methods in performing visual analysis tasks.

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